Bus Tickets from Gainesville, FL to Charleston, SC, US

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Previously seen trips

One passenger / one way

  • Departure time: August 24 at
    Departure city: Gainesville
    Departure location: Rosa Parks Station
    Arrival time: August 25 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 24 at
    Departure city: Gainesville
    Departure location: Gainesville Bus Stop
    Arrival time: August 24 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: Greyhound + FlixBus
    Greyhound + FlixBus
    Vehicle: BusDuration:

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Bus Gainesville, FL to Charleston, SC, US: Trip Overview

Average Ticket PriceUS$101
Average Bus Trip Duration13h 15m
Number of daily buses2
Earliest bus departure12:35am
Distance417 km
Latest bus departure10:40pm

Gainesville to Charleston Bus

With Busbud, comparing and booking tickets for a bus from Gainesville to Charleston is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

Bus service from Gainesville to Charleston will be provided by the most trusted bus companies.

Discover how much the bus trip from Gainesville to Charleston will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Gainesville, FL - Charleston, SC, US

  1. What is the travel distance from Gainesville to Charleston?

    Gainesville and Charleston are 417 km (259 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Gainesville to Charleston?

    Buses departing from Rosa Parks Station in Gainesville will take you to Charleston Bus Station in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-20
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08-21
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Today
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08-23
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08-24
US$57
08-25
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08-27
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busbud logoThe cheapest trip from Gainesville, FL to Charleston, SC, US was searched and found on Aug 24, 2025 with a price of US$57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Gainesville, FL to Charleston, SC, US, as early as possible.

You can expect to pay from US$57 to US$57 for a bus ticket from Gainesville, FL to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$57 which is on 2025-08-24.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Gainesville to Charleston.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Much more than a mere vehicle taking you from Gainesville to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Gainesville to Charleston will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Gainesville to Charleston while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Gainesville, FL by bus?

Bus from Charleston, SC, US to Gainesville, FL

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