Bus Tickets from Detroit, MI to Winston-Salem

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SunSep 7
from US$88
MonSep 8
TueSep 9
WedSep 10
ThuSep 11
FriSep 12
SatSep 13
SunSep 14

Cheap buses leaving Sunday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: September 7 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: September 8 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 7 at
    Departure city: Detroit
    Departure location: Detroit Bus Station
    Arrival time: September 8 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Detroit, MI to Winston-Salem: Trip Overview

Average Ticket PriceUS$110
Average Bus Trip Duration13h 55m
Number of daily buses2
Earliest bus departure6:40am
Distance734 km
Latest bus departure8:15pm

Detroit to Winston-Salem Bus

Busbud helps you find a bus from Detroit to Winston-Salem. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Detroit to Winston-Salem from the most reliable bus companies operating this trip.

Discover how much the bus trip from Detroit to Winston-Salem will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Detroit, MI - Winston-Salem

  1. What is the travel distance from Detroit to Winston-Salem?

    Detroit and Winston-Salem are 735 km (456 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Detroit to Winston-Salem?

    Buses departing from Detroit Bus Station in Detroit will take you to Winston Salem Greyhound Bus Station in Winston-Salem.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09-03
No data
09-04
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Today
US$105
09-06
No data
09-07
US$80
09-08
No data
09-09
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09-10
No data
busbud logoThe cheapest trip from Detroit, MI to Winston-Salem was searched and found on Sep 7, 2025 with a price of US$80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Winston-Salem, as early as possible.

You can expect to pay from US$80 to US$169 for a bus ticket from Detroit, MI to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$80 which is on 2025-09-07.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Detroit and Winston-Salem!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Detroit to Winston-Salem, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Detroit to Winston-Salem will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Detroit to Winston-Salem while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Will you be returning to Detroit, MI by bus?

Bus from Winston-Salem to Detroit, MI

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